Mercer professors from across the University have been awarded numerous competitive research grants during the past year. These prestigious grants enable faculty and students to conduct scholarly research that benefits the greater community. Below are details of a few of the grants Mercer faculty have been awarded. Also see below for a full listing of research grants awarded to Mercer faculty since June, provided by the Office of Grants and Contracts.
College of Liberal Arts
Dr. Arthur Salido, assistant professor of chemistry in Mercer’s College of Liberal Arts, was awarded a grant from the National Science Foundation (NSF). Totaling $102,000, the grant has enabled Mercer chemistry, environmental science and environmental engineering students to work with Inductively-Coupled Plasma Optical Emission Spectrometry— a cutting-edge instrument used in determining metals in samples and investigating air and water contamination.
The new lab instrument will also promote collaboration between Mercer undergraduates and local high school students, according to Salido. He said that with the addition of this new device to Mercer’s chemistry lab will enable Mercer to invite high school students to come to the University and to participate in college-level research.
One of Salido’s colleagues in the Chemistry Department was also awarded a competitive NSF Grant. Dr. Caryn Seney, associate professor of chemistry at Mercer, and Dr. Robin Bright of Fort Valley State University were awarded a three-year grant totaling $244,752 from NSF. Mercer will receive $178,552 of the total grant. The funding has allowed Mercer to purchase multiple types of lasers and detectors, which have been used to build a sensitive Raman spectrophotometer— an advanced instrument used in measuring light and molecular interactions.
With the addition of this new equipment, Mercer students are now immersed in a research environment similar to what they would experience in industry or graduate school, said Seney. Mercer senior Josh Yelverton is currently using the new equipment for his senior research project in which he is studying the interaction of antibodies and antigens. The grant will also enable undergraduate students to conduct summer research in Mercer’s chemistry lab.
School of Medicine
Dr. James L. Thomas, assistant professor of pharmacology in the Division of Basic Medical Sciences of the Mercer School of Medicine, received a grant of $928,000 from the National Institutes of Health. With this NIH award, Thomas is examining a new target protein for the treatment of breast and prostate cancer. His analysis of the enzyme allows for the design of inhibitors specific for the enzyme in tumors that will not also inhibit a different form of the enzyme in the adrenal gland. His study could lead to the development of better treatments for breast and prostate cancer.
Southern School of Pharmacy
At the Southern School of Pharmacy, Dr. Ajay K. Banga, professor and chairman of the Department of Pharmaceutical Sciences,was awarded grants totaling about $296,000 from Altea Therapeutics Corp. to conduct studies on a drug-delivery method called thermal microporation. The painless method involves creating microscopic holes in the skin much smaller than those created by a needle or syringe. With the grant, Banga will explore delivering hydromorphone and insulin using this method.
The pharmacy professor was also awarded a grant of $199,200 from the
European headquarters of Solvay Pharmaceuticals to explore delivering drugs through electrically activated skin patches, a process called iontophoretic delivery. If successful, Solvay will explore ways to bring the process to market with a strategic partner, Banga said. With both projects Banga will be working with Ph.D. students and post-doctoral scholars from the Southern School of Pharmacy.
A Sign of Excellence
“These exemplary projects are yet another indicator of the significance of the work of Mercer’s remarkable faculty,” said Dr. Priscilla Danheiser, associate provost for research and sponsored programs at Mercer. “It is wonderful to see the excellent and important work of Mercer’s teacher-scholars recognized by outside evaluators and extramural funding agencies, and it will be exciting to see the impact the projects will have on our students and the learning environment at Mercer as well as on the world beyond our university. ”
Research Grants Awarded – June 1, 2004 – March 1, 2005 |
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Principal Investigator |
Project Title |
Sponsor Name |
|
Ajay Banga |
Transdermal Delivery of Proteins and Peptides by thermal Microporation |
Altea Therapeutics |
|
Ajay Banga |
Transdermal Delivery of Small Molecules by Thermal Microporation |
Altea Therapeutics |
|
Ajay Banga |
Evaluation of Drug Formulations for Transdermal Delivery |
Undisclosed client |
|
Ajay Banga |
Screening of Therapeutic chemical/Biological Entities for Transdermal and/or Iontophoretic Delivery |
Solvay Pharmaceuticals, Inc. |
|
Ajay Banga |
Transdermal Delivery of Nicotine and its Salts – Issues and Innovations |
GlaxoSmithKline |
|
Ajay Banga |
Delivery of NSAIDs into Skin by Iontophoresis and Sampling by Microdialysis |
Travanti Pharma Inc. |
|
Christy Bridges |
Renal Uptake of Mercury |
National Institutes of Health/DHHS |
|
Michael Brown |
Molecular Determinants of Mitochondrial Optic Atrophy |
National Eye Institute/NIH/DHHS |
|
Mark Dorogy |
EVENT REGISTRY: A Prospective, Multicenter, Observational Registry to Evaluate the Incidence of Majo |
Baylor College of Medicine |
|
Martin D’Souza |
The Effect of Endothelial Uptake of Microencapsulated Anti-Sense Oligomers to NF-kB and Catalase on |
Dialysis Clinic |
|
Martin D’Souza |
Evaluation of the Effect of Microencapsulated Anti-Cytokine Drugs on Arthritis |
Dialysis Clinic |
|
Michael Jann |
Formulary Development and Periodic Update for the Georgia Division of Public Health Cancer State Aid |
Georgia Department of Human Resources |
|
Michael Jann |
Single-Dose Pharmacokinetics and Bioavailability of Cilostazol Capsule-05, Cilostazol Capsule-06, Ci |
Lipocine, Inc. |
|
Harold Katner |
ENHANCE Study – Protocol #ML 18021 “A 48-Week, Randomized, Open Label, Multicenter, Prospective Stu |
Roche Laboratories, Inc. |
|
Harold Katner |
A Phase II Open Label 48-Week Trial of TMC 114/RTV in HIV-1 Infected Subjects Who Failed Trial Tre |
Tibotec Pharmaceuticals, Ltd. |
|
Harold Katner |
Protocol Number AI 424128 A Phase IV, Multi-Center Cross Sectional Study to Evaluate the I50L Substi |
Bristol-Myers Squibb Company |
|
Laura Lackey |
Professional Ethics and Engineering: An Assessment Approach |
Colorado School of Mines |
|
Diane Matesic |
Action of Novel Anti-Tumor Agents on Cell Communication |
National Institutes of Health/DHHS |
|
Philip McCreanor |
Florida Bioreactor Landfill Demonstration Project: 2005 |
University of Central Florida |
|
Janet Piskurich |
Induction of CIITA Expression in B Cells and Myeloma |
National Institutes of Health/DHHS |
|
Arthur Salido |
Implementation of Inductively Coupled Plasma Optical Emission Spectrometry in Chemistry, Environment |
National Science Foundation |
|
Caryn Seney |
RUI-Studies of Antigen/Antibody Interactions with Colloidal Particles |
National Science Foundation |
|
Samuel Shillcutt |
DHR Contract – MHDDAD (Mental Health, Developmental Disabilities and Addictive Diseases)) |
Georgia Department of Human Resources |
|
Samuel Shillcutt |
A Multicenter Randomized, Double-Blind, Study on the effect of Aripiprazole on Overweight Patients T |
Bristol-Myers Squibb Pharmaceutical Research Institute |
|
Jeffrey Stephens |
A Randomized Prospective Study of the Efficacy, Safety, and Tolerability of Two Doses of GW433908/Ri |
GlaxoSmithKline |
|
James Thomas |
Placental 3 beta-Hydroxysteroid Dehydrogenase/Isomerase |
National Institutes of Health/DHHS |
|
Joanna Watson |
Native American Graves Protection and Repatriation Action Plan for a Multiple National Monument Cont |
National Park Service/Department of the Interior |
|
Rudolfs Zalups |
Metallothioneiin, Mercury and Monocyte Activation |
National Institutes of Health/DHHS |
|
Rudolfs Zalups |
Transport and Toxicity of Mercury in the Nephron |
National Institute of Environmental Health Sciences/NIH/DHHS |